What’s the best wager to make, considering each of the 16 matchups on the NFL’s Week 18 slate? Our favorite point-spread choice is Eagles -3, but we have lots more tips for you, which could lead to parlay possibilities, in this article.

Take advantage of our predictions to make your NFL picks this week. BetMGM has all the information you need to begin betting on the NFL.

Best Week 18 Spread Bets

Jump to Matchup:

MIA-NYJ | CIN-PIT | HOU-TEN | BUF-NE | NYG-PHI

Pick: Dolphins -1 vs. Jets

• Matchup: Miami Dolphins at New York Jets
• Projected Winner & Margin: Dolphins by 1.6 points (Bet on this game at BetMGM)
• Spread: Dolphins -1
• Time: 4:25 p.m. ET
• Date: Jan. 5
• TV Channel: FOX
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Steelers +1.5 vs. Bengals

• Matchup: Cincinnati Bengals at Pittsburgh Steelers
• Projected Winner & Margin: Steelers by 5.8 points (Bet on this game at BetMGM)
• Spread: Bengals -1.5
• Time: 8 p.m. ET
• Date: Jan. 4
• TV Channel: ABC/ESPN
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Texans +1.5 vs. Titans

• Matchup: Houston Texans at Tennessee Titans
• Projected Winner & Margin: Texans by 8.2 points (Bet on this game at BetMGM)
• Spread: Titans -1.5
• Time: 1 p.m. ET
• Date: Jan. 5
• TV Channel: CBS
• Live Stream: Paramount+ | Fubo (Regional restrictions may apply)

Pick: Bills -2.5 vs. Patriots

• Matchup: Buffalo Bills at New England Patriots
• Projected Winner & Margin: Bills by 20.5 points (Bet on this game at BetMGM)
• Spread: Bills -2.5
• Time: 1 p.m. ET
• Date: Jan. 5
• TV Channel: CBS
• Live Stream: Paramount+ | Fubo (Regional restrictions may apply)

Pick: Eagles -3 vs. Giants

• Matchup: New York Giants at Philadelphia Eagles
• Projected Winner & Margin: Eagles by 26.0 points (Bet on this game at BetMGM)
• Spread: Eagles -3
• Time: 1 p.m. ET
• Date: Jan. 5
• TV Channel: CBS
• Live Stream: Paramount+ | Fubo (Regional restrictions may apply)

Make smart decisions. Use those stats when making your NFL picks and place your bet on BetMGM.

Best Week 18 Total Bets

Jump to Matchup:

Under 56.5 – Vikings vs. Lions

• Matchup: Minnesota Vikings at Detroit Lions
• Projected Total: 49.7 points (Bet on this game at BetMGM)
• Time: 8:20 p.m. ET
• Date: Jan. 5
• TV Channel: NBC
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Over 40 – Chiefs vs. Broncos

• Matchup: Kansas City Chiefs at Denver Broncos
• Projected Total: 42.8 points (Bet on this game at BetMGM)
• Time: 4:25 p.m. ET
• Date: Jan. 5
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Over 39 – Seahawks vs. Rams

• Matchup: Seattle Seahawks at Los Angeles Rams
• Projected Total: 43.3 points (Bet on this game at BetMGM)
• Time: 4:25 p.m. ET
• Date: Jan. 5
• TV Channel: FOX
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Over 41 – Bears vs. Packers

• Matchup: Chicago Bears at Green Bay Packers
• Projected Total: 43.3 points (Bet on this game at BetMGM)
• Time: 1 p.m. ET
• Date: Jan. 5
• TV Channel: FOX
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Over 43.5 – Saints vs. Buccaneers

• Matchup: New Orleans Saints at Tampa Bay Buccaneers
• Projected Total: 47.8 points (Bet on this game at BetMGM)
• Time: 1 p.m. ET
• Date: Jan. 5
• TV Channel: FOX
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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